​Patients on the NSW Opioid Treatment Program (OTP) may be transferred from methadone to buprenorphine. There are three ways for health professionals to enable this transfer:
- Direct transfer (conventional method)
- Buprenorphine micro-dosing
- Bridging with a short-acting opioid

When using direct transfer, prescribers should refer to the
NSW Clinical Guidelines – Treatment of Opioid Dependence.

 

Micro-dosing and bridging

When using the micro-dosing or bridging methods, prescribers should refer to the NSW Interim Clinical Guidance – Outpatient Transfer from Methadone to Buprenorphine Using the Micro-dosing or Bridging Methods.


The evidence base for the micro-dosing and bridging methods is still developing. Use of opioid agonist treatment medications in this context is considered off-label and must be undertaken in accordance with:

  • local clinical governance procedures
  • legislation, policies or procedures that govern off-label prescribing

The following prescribers are eligible to undertake micro-dosing and bridging:

  •  Addiction Medicine Specialists and Addiction Psychiatrists
  •  Other medical practitioners who are OTP accredited
  • Nurse practitioners who are OTP accredited and work in public or Justice Health & Forensic Mental Health Network settings
Current as at: Thursday 6 April 2023