A white tablet containing a nitazene (protonitazene) has caused severe opioid overdose in Sydney

​A severe opioid overdose has occurred after taking a white tablet.

The tablet was described as containing LSD or magic mushroom.

Blood tests detected protonitazene, a potent synthetic opioid.

Last updated: 07 February 2025
Download

K​n​​ow the risks
​​​ 

  • Nitazenes, such as protonitazene, are synthetic opioids that are stronger and may be longer acting than many other opioids. They are up to 500 times more potent than heroin.
  • Nitazenes are dangerous and vary in effect - some nitazenes are so potent that there is no safe dose. The purity can also vary within a single batch.
  • Nitazene use has been linked to death and other serious harms in NSW.
  • The risks of overdose are increased if you:
    • Use drugs alone.
    • Use nitazenes or other opioids if you have not used them before.
    • Use drugs again after a break.
    • Use with other drugs (like alcohol, benzodiazepines, ketamine or GHB).
    • Use a new batch.

Effects to look out for

  • Pin-point pupils, drowsiness, loss of consciousness, slow breathing/snoring or skin turning blue/grey.
  • If you or others experience these symptoms, get help immediately.

Getting help

  • If you or your friends see the warning signs of overdose:
  • Seek help immediately from your nearest emergency department or call Triple Zero (000). You won’t get into trouble for seeking medical care.
  • Start CPR if someone is not breathing.
  • Use naloxone if you have it. Call '000' even if naloxone has been given.

Take Home Naloxone program

  • Naloxone is a life-saving medicine that can temporarily reverse an opioid overdose. Naloxone is available in an easy to use nasal spray, and as a pre-filled injection. With basic training, it can be administered by anyone.

  • The effects of naloxone may wear off, and ongoing doses and hospital treatment may be needed.

  • You should carry naloxone if:

    • You are using drugs such as cocaine, ketamine, methamphetamine, MDMA, benzos, or opioids.
    • You are hosting or going to a party where drugs will be present.
  • If you might experience or witness an opioid overdose you can get naloxone for free without a prescription in NSW from many community pharmacies, needle and syringe programs, opioid treatment services and NUAA.
  • Visit Your R​oom to find out where you can get naloxone and for more information on take home naloxone.
  • NUAA can mail you naloxone in a discreet package. Order via their online shop: shop.nuaa.org.au or call (02) 9171 6650.

Support and advice

For free and confidential advice:

 

 

Current as at: Friday 7 February 2025